Evaluation of approaches for identifying population informative markers from high density SNP Chips
نویسندگان
چکیده
منابع مشابه
Evaluation of ten SNP Markers for Human Identification and Paternity Analysis in Persian Population
Background: DNA markers are inevitable tools of human identification in forensic science. Single Nucleotide Polymorphisms (SNPs) are one category of these markers which is concerned to use especially in the case of degraded DNA because of their short amplicons. Objectives: Detection of highly informative SNPs by the criteria is the essential step to devel...
متن کاملGenetic Diversity and Population Structure of Ethiopian Sheep Populations Revealed by High-Density SNP Markers
Sheep in Ethiopia are adapted to a wide range of environments, including extreme habitats. Elucidating their genetic diversity is critical for improving breeding strategies and mapping quantitative trait loci associated with productivity. To this end, the present study investigated the genetic diversity and population structure of five Ethiopian sheep populations exhibiting distinct phenotypes ...
متن کاملFinding Markers That Make a Difference: DNA Pooling and SNP-Arrays Identify Population Informative Markers for Genetic Stock Identification
Genetic stock identification (GSI) using molecular markers is an important tool for management of migratory species. Here, we tested a cost-effective alternative to individual genotyping, known as allelotyping, for identification of highly informative SNPs for accurate genetic stock identification. We estimated allele frequencies of 2880 SNPs from DNA pools of 23 Atlantic salmon populations usi...
متن کاملAscertainment biases in SNP chips affect measures of population divergence.
Chip-based high-throughput genotyping has facilitated genome-wide studies of genetic diversity. Many studies have utilized these large data sets to make inferences about the demographic history of human populations using measures of genetic differentiation such as F(ST) or principal component analyses. However, the single nucleotide polymorphism (SNP) chip data suffer from ascertainment biases ...
متن کاملSimultaneous QTL detection and genomic breeding value estimation using high density SNP chips
BACKGROUND The simulated dataset of the 13th QTL-MAS workshop was analysed to i) detect QTL and ii) predict breeding values for animals without phenotypic information. Several parameterisations considering all SNP simultaneously were applied using Gibbs sampling. RESULTS Fourteen QTL were detected at the different time points. Correlations between estimated breeding values were high between m...
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ژورنال
عنوان ژورنال: BMC Genetics
سال: 2011
ISSN: 1471-2156
DOI: 10.1186/1471-2156-12-45